cataliesw
45 posts
Oct 27, 2024
11:40 PM
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Targeting transgenes to a chosen location in the genome has a number of advantages. A single copy of the DNA construct can be inserted by targeting into regions of chromatin that allow the desired developmental and tissue-specific expression of the transgene. The ROSA26 locus is such a genomic site that is ideal to integrate a transgene of interest for stable expression. Learn more: rosa26 mouse
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