No, Lost Mary vapes are designed to be disposable and are not refillable. These devices come pre-filled with e-liquid and are meant for one-time use. Once the vape runs out of juice or battery, it should be properly disposed of and replaced with a new one. Attempting to refill a Lost Mary vape can damage the device and may lead to leaks or malfunction. If you're looking for a reusable option, consider a refillable pod system instead.